Cut to the Chase: In Favor of Empiric Therapy for PA
Jenifer Brown, MD
Harvard University
Primary aldosteronism (PA) is the most common cause of endocrine hypertension, affecting at least 10% of individuals with hypertension, and 25% of those with treatment resistant hypertension. PA represents an independent risk factor for cardiovascular morbidity and mortality. Targeted PA therapy can circumvent such cardiovascular complications. Due to the high PA prevalence, testing complexity, and resource limitations, some hypertension experts have proposed empiric therapy with mineralocorticoid receptor antagonists (MRA) as an alternative to formal PA diagnosis. This session will discuss the pros and cons of empiric MRA therapy vs. formal diagnosis and individualized PA treatment.
Jenifer Brown, MD
Harvard University
Paolo Mulatero, MD
University of Torino
Adina Turcu, MD, MS
University of Michigan